Samma Rule ended with their defeat by Arghun Dynastity in 1521 A.D. (23) Tarkhan took over the power in Sindh in 1554.[24] The imperial Forces of Akbar took over Sindh in 1590 and this country was ruled by Mughal Governors [25] till coming of Kalhoras in power in 1700 A.D. (26)

During this period (1521-1700 A.D) Sindh witnessed and experienced so many important events and happenings. Such as taking refuge by Dara Shikoh, entering Sindh by European adventures, establishing trade in Sindh by the Dutch in 1652 and the establishment of factory by English people in 1635.

The period under study was terrible time for Sindh people. Therefore, most of people opted to migrate elsewhere. Some of them migrated to Punjab and some of them went to Burhanpur. All Sindhis, either Muslims, or Hindus, were in trouble. The only aim of governance by rulers was exploitation of Sources and Resources of Sindh, to suppress people and to use iron hand in every affair to keep people silent under the shadow of their highhandedness. Lives and property of people was not safe and everybody was feeling unsafe in all three regimes.

 In such a horrific situation, Sindhis were not in favor to afford Hindu-Muslim differences. Communalism never took place in these days.  However, an amazing event took place in this period and that was not between Sindhi Hindus and Sindhi Muslims, but it was between a ruling figure and Hindus.

Dayaram Didumal in his book has given an account of erecting of Minaret of Mir Masum Shah in Sukkur. He was the Governor of Bakkar appointed by Mughal Emperor Akbar.   Dayaram Gidumal writes that Mir Masoom fall in love with a beautiful Hindu girl. The lady refused to wed to him. Mir Masoom Shah decided to erect a Minaret in the memory of his friendship. The Minaret was built in 1607. He used to see his absentee dear from the top of the minaret, daily. (27)

This event throws light on the social status of Hindu segment of Sindh society and provides sufficient proof to believe that Hindus were accepted with respect and their religious honor and dignity and never faced any risk from Muslim Rulers and Sindhi segment of Society.